Dr. Malcolm Sayer, a shy research physician, uses an experimental drug to "awaken" the catatonic victims of a rare disease. Leonard is the first patient to receive the controversial treatment. His awakening, filled with awe and enthusiasm, proves a rebirth for Sayer too, as the exuberant patient reveals life's simple but unutterably sweet pleasures to the introverted doctor.

Director: Penny Marshall

Cast: Robert De Niro, Robin Williams, John Heard, Julie Kavner, Penelope Ann Miller, Ruth Nelson, Max von Sydow, Anne Meara, Dexter Gordon, George Martin, Alice Drummond, Richard Libertini, Laura Esterman, Barton Heyman, Judith Malina, Mary Alice, Keith Diamond, Bradley Whitford, John Christopher Jones, Mary Catherine Wright